Ph.D. KeunMin Ken Lee

Ph.D. KeunMin Ken Lee

(he/him)

Biophysicist and AI Researcher

KBRI

Professional Summary

KeunMin Ken Lee is a Biophysicist and AI Researcher at the Korea Brain Research Institute (KBRI). His research sits at the intersection of classical biophysics and modern machine learning, with a focus on developing novel tools to understand neurodegenerative diseases.

Drawing from his award-winning Ph.D. work at KAIST on molecular fractionation by diffusion, his current projects involve building multimodal AI systems and investigating the liquid-liquid phase separation of Tau proteins in the context of Alzheimer’s Disease. He holds both a Ph.D. in Bio and Brain Engineering and a B.S. in Physics from the Korea Advanced Institute of Science and Technology (KAIST).

Outside of the lab, he is a passionate tech enthusiast who enjoys building custom PCs and self-hosted servers, and is also an avid DJ and vinyl collector.

Education

MS and PhD Joint Program Bio and Brain Engineering

Korea Advanced Institute of Science and Technology

BS Physics

Korea Advanced Institute of Science and Technology

Interests

AI tools for Medical Applications Diffusion Theory Protein Purification Neuroscience Alzheimer’s Disease and Tau Proteins Liquid-Liquid Phase Separation
📚 My Research

My research mission is to decode the fundamental principles of biological systems by building bridges between physics, neuroscience, and artificial intelligence. I develop novel AI models to interpret complex, high-dimensional neural data, such as EEG and fMRI, with the goal of revealing the underlying biophysical mechanisms of neurodegenerative diseases.

Ultimately, I aim to extend this fundamental understanding of biology to new frontiers, exploring how life operates and adapts in extreme environments. By creating robust, data-driven models of terrestrial biology, we can lay the groundwork for the next era of research in space. I am always looking for new collaborations at this exciting intersection of fields.

Recent Publications
(2024). Fractionation by Spatially Heterogeneous Diffusion: Experiments and the Two-Component Random Walk Model. Journal of the American Chemical Society.
DOI
(2024). Water Hydrogen-Bond Mediated Layer by Layer Alignment of Lipid Rafts as a Precursor of Intermembrane Processes. Journal of the American Chemical Society.
(2023). Synchrotron X-ray study of intrinsically disordered and polyampholytic Tau 4RS and 4RL under controlled ionic strength. European Physical Journal E.